A Clinical Study to Help Older Adults Stay Energetic and Active
Research Centre: PARC Clinical Research
Location: Level 4C, Royal Adelaide Hospital, 1 Port Road, Adelaide SA 5000
Lead Researcher: Guy Ludbrook
HREC Committee: This study has been reviewed and approved by the Bellberry Limited Human Research Ethics Committee
Low energy and decreased physical activity are common complaints among older adults. Researchers are working on therapies to prevent and treat these problems so that people can stay energetic and active as they age.
Unexplained anaemia of aging (UAA) is an important condition that can lead to low energy, poor physical function, increased risk of falls, and decreased quality of life. UAA is a type of anaemia (not enough red blood cells in your blood) where no definitive underlying condition can be found and the cause is thought to be ageing itself. In fact, nearly 1/3 of people aged 65 years old and up with anaemia have UAA. However, UAA is often underrecognized and left untreated. Doctors and researchers believe that it is essential to develop new therapies to treat UAA, since standard treatments (such as vitamins and iron supplements) are not effective.
The aim of this clinical study is to test a new therapy, which may improve energy levels, quality of life, and activity levels in older adults who have UAA.
- You may feel more energetic and more able to participate in physical activities.
- You may contribute valuable information that may help our understanding of an important health condition.
- You will receive regular monitoring from healthcare professionals.
- There is no cost to you to participate in the study. Travel expenses will be reimbursed.
Who Can Participate?
- Adults aged 65 or older who have Unexplained Anaemia of Aging (UAA).
- You may have UAA if:
- You have anemia, or believe you may have anemia AND
- You commonly feel tired or have low energy levels AND
- Your anemia is not explained by a clear cause
- If you meet the above criteria, please fill out the survey and one of our research sites will contact you for further evaluation.
- Participants must be able to:
- Attend 16 study visits at the research site over approximately 3 months AND
- Have weekly blood draws at these visits
- The study treatment is a pill that’s taken by mouth.
- Medications similar to this one have been shown to be safe and are being used to treat anaemia in patients with kidney disease.
- You will have the chance to wear an activity monitor device that keeps track of your steps and movements
- Your records relating to this study and any other information received will be kept strictly confidential, unless we are legally obligated to disclose this information.
- If you decide to participate in the study and later feel you no longer wish to be part of it, you may stop at any time.
About the Research Centre:
PARC Clinical Research
PARC is a University of Adelaide based research group conducting specialised research into multiple disciplines, led by Professor Guy Ludbrook. The purpose of the Unit is not only to undertake contract clinical research for the pharmaceutical and biotech industries, but also to provide a safe and suitable environment for the conduct of academic clinical studies. PARC has extensive experience in the conduct of clinical research with compounds of narrow therapeutic index – such as opioids and products in early phase of development that require specialised management.
Due to the current situation with the COVID-19 pandemic, the researchers would like to assure the participants that ensuring the safety of the participants as well as the study staff is of utmost importance.