The AMAZES Study: Asthma and Macrolides: the Azithromycin Efficacy and Safety Study (Concord, Sydney)

Please note: This trial has finished recruiting and is not accepting new participants.
Research Centre:
Concord Repatriation General Hospital
Hospital Road, Concord West, NSW (click for map)
Lead Doctor:
Professor Christine Jenkins & A/Prof Matthew Peters
Ethics Committee:
Approved by the Hunter New England Health Research Ethics Committee


The AMAZES Study research team is aiming to determine whether taking an antibiotic (Azithromycin) alongside normal asthma medications helps to reduce the number of asthma ‘attacks’ and general daily symptoms experienced by adults with asthma. Those patients for whom this study is suitable, will be randomly allocated to take either Azithromycin or placebo tablets over a 48-week period (neither participants nor investigators will know which medication is being taken until the end of the study). Participants will have their asthma closely monitored over the 48-week period and monitoring will continue for an additional 4 weeks after the treatment has ended. Participants will not need to stop taking their regular asthma medication.

Who Can Participate?

  • Adults with asthma (aged 18 and over)
  • who are non-smokers (or ex smokers) and
  • who experience symptoms despite taking regular preventer medication

What Next?

  1. Click the link below to enter your contact details and answer some eligibility questions.
  2. The research centre will then contact you by phone to discuss the trial and answer your questions.
Click Here to Enter Your Contact Details and Be Contacted by Phone About the Trial