Adults Struggling with Depression and Alcohol Use? This Potential New Treatment May Help!

Research Center: VA Connecticut Healthcare System
Location: 950 Campbell Ave, West Haven, CT 06516
Lead Doctor: Gihyun Yoon, M.D.
IRB Committee: This study has been reviewed and approved by the Human Studies Subcommittee.


Depression and Alcohol Use Disorder (AUD) frequently co-occur – about 40% of people with depression are likely to also have AUD in their lifetime.

This research study is testing the effectiveness of a combination of medications in reducing alcohol consumption and symptoms of depression. These medications have already been approved by the FDA for a different use and have shown promise in reducing symptoms of depression.

This study is looking for adults aged 21 to 65 years old who have depression and at the same time struggle with alcohol use. Participants are required to attend 11 study visits at the research center over approximately 5 months and will receive up to $520 for participating.

Why Participate? 

  • You may experience a reduction in your alcohol craving or alcohol consumption.
  • You may experience an improvement in your depression symptoms.
  • You will be compensated $520 for participating in this study.
  • You will be helping to advance medical research aimed at improving treatments for depression and alcohol use disorder.

Your Rights

  • If you decide to participate in the study and later feel that you no longer wish to be part of it, you may withdraw at any time.
  • Your records relating to this study and any other information received will be kept strictly confidential, except as required by the law.
  • Qualified health professionals will monitor your health as it relates to the study.

Who Can Participate?

  • Adults aged 21 to 65 years old who have depression and struggle with alcohol use
  • Must have at least 4 heavy drinking sessions in the past month. 
  • Able to attend 11 study visits at the research site over approximately 5 months.

What Next?

  1. Click the link below to enter your contact details and answer some eligibility questions.
  2. The research centre will then contact you by phone to discuss the trial and answer your questions.
Click Here to Enter Your Contact Details and Be Contacted by Phone About the Trial