Is Your Current Depression Treatment Not Enough?

Please note: This trial has finished recruiting and is not accepting new participants.

Research Center: Lindner Center of HOPE
Location: 4075 Old Western Row Rd Mason OH 45040
Lead Doctor: Dr. Susan L. McElroy
IRB Committee: This study has been reviewed and approved by the Western Institutional Review Board


Major Depressive Disorder is a leading cause of disability in the United States. While there are options available, finding a treatment that works best for an individual can be a long and costly process. Many also find that their current treatment does not provide them adequate relief from their depression symptoms.

This study explores if a new investigational medication, Rapastinel, can treat symptoms of a major depressive episode while a participant is currently on a stable dose of another antidepressant therapy.

This study seeks men and women who currently suffer from MDD and are currently taking only one antidepressant. Participants are required to attend 11-12 study visits at the research site over approximately a 6 week period and will be reimbursed $75 per completed visit for travel and related expenses.

Why Participate?

  • You will be helping to advance medical research.

Your Rights

  • If you decide to participate in the study and later feel that you no longer wish to be part of it, you may withdraw at any time.
  • Your records relating to this study and any other information received will be kept strictly confidential, except as required by the law.
  • Qualified health professionals will monitor your health as it relates to the study.

Who Can Participate?

  • Men and women aged 18-65 who are currently experiencing symptoms of MDD
  • Are only taking one antidepressant.  
  • Have felt depressed for at least 2 months
  • Must be comfortable with needles
  • Have not been diagnosed with Bipolar disorder, a Personality disorder or a psychotic disorder
  • Are not currently participating in another clinical trial
  • Able to attend 11-12 study visits at the research site over approximately 6 weeks

What Next?

  1. Click the link below to enter your contact details and answer some eligibility questions.
  2. The research centre will then contact you by phone to discuss the trial and answer your questions.
Click Here to Enter Your Contact Details and Be Contacted by Phone About the Trial