Stress-Induced Alcohol Use Disorder Study

Research Center: VA Connecticut Healthcare System/Yale University
Location: 950 Campbell Ave, West Haven, CT, 06516
Lead Doctor: Dr. Elizabeth Ralevski
IRB Committee: This study has been reviewed and approved by the Yale University/VA Institutional Review Board


A study is investigating how allopregnanolone (ALLO) influences the effects of alcohol in people with alcohol use disorder. 

ALLO is a product of the hormone progesterone and is found naturally in your body. Considerable evidence suggests that ALLO helps regulate receptors in the brain responsible for stress response thus affecting one’s tolerance of, dependence on and withdrawal from alcohol triggered by stress.

This study seeks men and women who consumes alcohol at least 3 days per week. Participants are required to attend 2 study visits at the research site over a 2-month period and will be compensated $210 for participating in this study.

Why Participate? 

  • You will be compensated up to $210 for participating in this study.
  • You will be helping to advance medical research on alcohol use disorder.

Your Rights

  • If you decide to participate in the study and later feel that you no longer wish to be part of it, you may withdraw at any time.
  • Your records relating to this study and any other information received will be kept strictly confidential, except as required by law.
  • Qualified health professionals will monitor your health as it relates to the study.

Who Can Participate?

  • Men and women aged 21-50 who suffer from alcohol use disorder.
  • Able to attend 2 study visits at the research site over approximately 2 months.
  • Not currently seeking treatment for alcohol use disorder.
  • Has no other substance abuse disorder.

What Next?

  1. Click the link below to enter your contact details and answer some eligibility questions.
  2. The research centre will then contact you by phone to discuss the trial and answer your questions.
Click Here to Enter Your Contact Details and Be Contacted by Phone About the Trial