Study Explores Behavioral Intervention to Help Reduce Cigarette Cravings

Research Center: Medical University of South Carolina
Location: 125 Doughty Street, Charleston, South Carolina (downtown Charleston)
Lead Doctor: Dr. Michael Saladin
IRB Committee: This study has been reviewed and approved by the Medical University of South Carolina Institutional Review Board


While statistics show that the overall number of cigarette smokers has declined from 20.9% in 2005 to 15.5% in 2016, cigarette smoking remains the leading preventable cause of disease and death in the United States.

The Medical University of South Carolina is conducting a study of smokers. The purpose of this study is to see if a new behavioral therapy might help to reduce urges to smoke and responses to smoking cues (e.g., seeing a pack of cigarettes) in men and women who smoke.

This study seeks men and women who currently smoke cigarettes. Participants are required to attend 12 study visits at the research site over a 6-month period and will be compensated for participating in this study.

Why Participate? 

  • You may experience a potential reduction in craving to smoke.
  • You may completely abstain from smoking.
  • You may get a referral for additional treatment outside of the study.
  • You will be compensated for participating in this study.
  • You will be helping to advance research on nicotine dependence.

Your Rights

  • If you decide to participate in the study and later feel that you no longer wish to be part of it, you may withdraw at any time.
  • Your records relating to this study and any other information received will be kept strictly confidential, except as required by law.
  • Qualified health professionals will monitor your health as it relates to the study.

Who Can Participate?

  • Men and women aged 25-65 who currently smoke at least 8 cigarettes per day and want to stop their cigarette use.
  • Able to attend 12 study visits at the research site located at MUSC over approximately 6 months. Please note for study visits: 
    • All participants must organize their own transport to the study visits. There is a free parking lot available on site for participants.
    • Participants are asked to abstain from cigarettes, alcohol, and drugs during the beginning stages of the study. 
    • Abstaining from smoking is only required for the first 5 visits. Participants are permitted to smoke if they so choose for the duration of the study after the 4 back-to-back training session days (the longest period of not smoking is 4 full days)
  • Willing to stop any current treatment for nicotine addiction.
  • Not using smokeless tobacco.

Note: All drug screens in this study are 100% for the purpose of this study and are confidential. Results will not be shared with anyone outside of the research staff and no participant is at risk of consequences if their drug screen is positive

What Next?

  1. Click the link below to enter your contact details and answer some eligibility questions.
  2. The research centre will then contact you by phone to discuss the trial and answer your questions.
Click Here to Enter Your Contact Details and Be Contacted by Phone About the Trial