Research Center: Macquarie University Hospital; Australian Alzheimer’s Research Foundation
Location: 2 Technology Place, Macquarie Park NSW 2113; U2/142 Stirling Highway Nedlands, WA 6009
Lead Doctors: Dr. David Gillatt; Dr. Roger Clarnette
Ethics Committee: This study has been reviewed and approved by Ramsay Health Care WA|SA Human Research Ethics Committee; Macquarie University Human Research Ethics Committee

Background

Alzheimer’s disease (AD) is the most common type of dementia which is the second leading cause of death of Australians. 

Experts believe that prevention is the best intervention for Alzheimer’s disease given that current knowledge suggests that the brain changes commence 20 to 30 years before the onset of symptoms. This study aims to establish the effectiveness of a testosterone and fish oil intervention to prevent the development of AD. It is called the TotAL Study (Testosterone and Omega Three – Amyloid Lowering).

This study seeks elderly men who are concerned about their memory. Participants are required to attend up to 13 study visits at the research centre over a period of approximately 14 months. A close family member or friend is also required to accompany the participant during the initial and final study visit.

Why Participate? 

• You may experience an improvement in your memory.
• Study-related procedures and tests will be provided to you for free.
• You will be helping to advance Alzheimer’s medical research.

Your Rights

• If you decide to participate in the study and later feel that you no longer wish to be part of it, you may withdraw at any time.
• Your records relating to this study and any other information received will be kept strictly confidential, except as required by the law.
• Qualified health professionals will monitor your health as it relates to the study.

Who Can Participate?

• Men aged 60-80 who are concerned about their memory
• Has a friend or family member who spends at least 5 hours per week with the participant and is willing to attend 2 study visits with the participant
• Able to attend up to 13 study visits at the research site over approximately 14 months