Help Advance Researchers Understand How Metformin Interacts With The Body

Research Centre: Adelaide Medical School, University of Adelaide
Location: Level 5 AHMS Building, North Terrace, Adelaide
Lead Researcher: Dr Tongzhi Wu
Ethics Committee: This study has been reviewed and approved by Central Adelaide Local Health Network Human Research Ethics Committee


Around 1.7 million Australians have Type 2 Diabetes, many of whom are managing their diabetes with a medication called metformin. 

This study is investigating how metformin interacts with bile acid from the gallbladder. Having a better understanding of these interactions will allow researchers understand the mechanisms of Metformin more precisely and introduce new improved therapies for diabetes in the future.

This study seeks men and women who are diagnosed with Type 2 Diabetes and manage their diabetes by diet only. Participants are required to attend a minimum of 4 study visits at the research site over a month period and will receive an honorarium of $20 per hour for their participation in this study.

Why Participate?

  • You will be helping to advance Type 2 Diabetes medical research.
  • You will receive an honorarium of $20/hour (~$500 for the entire study).

Your Rights

  • If you decide to participate in the study and later feel that you no longer wish to be part of it, you may withdraw at any time.
  • Your records relating to this study and any other information received will be kept strictly confidential, except as required by the law.
  • Qualified health professionals will monitor your health as it relates to the study.

Who Can Participate?

  • Men and women aged 18 – 75 years old.
  • Have been diagnosed with Type 2 Diabetes and managing their diabetes with diet only.
  • Able to attend a minimum of 4 study visits at the research site over 4 weeks. 
  • Willing to have a soft flexible tube inserted through your nose into the gut.

Please note:

Due to the current situation with COVID-19 pandemic, the study team would like to point out the following:

  • The research site does not treat COVID-19 patients and/or suspected COVID-19 patients.
  • The research site’s waiting area is spacious enough that participants will not be within close proximity to each other.
  • Hand sanitizers are available at the research site.
  • The research staff adheres to strict hygienic practices as well as other safety measures to prevent the spread of COVID-19.
  • Any staff suspected to have COVID-19, or has come into contact with someone who has COVID-19, will automatically undergo a voluntary quarantine for 14 days.
  • Interested participants will not be left waiting for a long period of time and will be quickly attended to.
  • The research site/institution is taking all precautionary measures to ensure the safety of the study participants.

What Next?

  1. Click the link below to enter your contact details and answer some eligibility questions.
  2. The research centre will then contact you by phone to discuss the trial and answer your questions.
Click Here to Enter Your Contact Details and Be Contacted by Phone About the Trial