Help Improve Treatments For Depression
Please note: This trial has finished recruiting and is not accepting new participants.
Research Centre: Yale University & National Center for PTSD
Location: The VA Hospital at 950 Campbell Avenue, West Haven, CT & 300 Cedar Street, New Haven, CT
Lead Doctor: Dr Chadi Abdallah
Ethics Committee: This study has been reviewed and approved by the Yale Human Investigation Committee
It is believed that most people with depression have a serotonin imbalance in the brain. As a result, existing antidepressants are focused on increasing serotonin levels to relieve symptoms. Unfortunately, these treatments are not always effective for everyone.
This research study is investigating whether a different ‘type’ of depression exists, where an imbalance of a chemical other than serotonin is contributing to depression symptoms. If another type of depression exists, specific treatments can be developed to address these imbalances and help people who do not benefit from existing antidepressants.
This study seeks people who currently suffer from depression. Participants are required to attend 3 study visits at the research site over 3 months and will be compensated up to $600 for participating in this study. Dependant on individual needs, participants may be reimbursed for mileage, be provided with cab/train/airfare up front, and/or be provided a hotel stay to be able to attend study visits.
Benefits to Participation
- You will be helping to advance medical research aimed at improving treatments for depression.
- You will receive a thorough medical and psychiatric evaluation at no cost to you.
- You will be compensated up to $600 for participating in this study.
- You will receive lunches at the study visits.
- Dependant on individual needs, participants may be reimbursed for mileage, be provided with cab/train/airfare up front, and/or be provided a hotel stay to be able to attend study visits.
- If you decide to participate in the study and later feel that you no longer wish to be part of it, you may withdraw at any time.
- Your records relating to this study and any other information received will be kept strictly confidential, except as required by the law.
- Qualified health professionals will monitor your health as it relates to the study.
Who Can Participate?
- Men and women aged 18 – 65 years old
- Currently experiencing symptoms of depression (for example low mood, trouble concentrating and sleeping, lack of energy)
- Have not been diagnosed with bipolar disorder
- Willing to undergo 2 Magnetic Resonance Imaging (MRI) scans
- Able to attend 3 study visits at the research site over 3 months