Research Center: Joslin Diabetes Center
Location: 1 Joslin Place, Boston, MA
Lead Researcher: Dr. Sarah Lessard
IRB: This study has been reviewed and approved by the Joslin Diabetes Center Committee on Human Studies Institutional Review Board

Diabetes among US adults is becoming increasingly common, says the Center for Disease Control and Prevention (CDC). Type 1 diabetes is a chronic condition where the body makes little or no insulin. This causes high blood sugar, which can lead to serious health complications if untreated.

High blood sugar in type 1 diabetes is managed by taking insulin as a medication. People with this condition are also advised to follow a healthy diet and do regular exercise. However, those with type 1 diabetes are less likely to see the benefits of exercise than those whose blood sugar levels are normal. Researchers want to understand why this is, so that they may learn how to maximize the health benefits of exercise for people with type 1 diabetes. This research study seeks to understand how blood sugar levels affect people’s response to exercise among adults with Type 1 diabetes.

• Participants may learn more about their body composition, fitness level, and health markers.
• Compensation will be provided to eligible participants for each study visit they attend.
• Participants will be contributing valuable information that may benefit those with Type 1 diabetes in the future.
• Participants will be helping to advance medical research.

• If you decide to participate in the study and later feel that you no longer wish to be part of it, you can withdraw at any time.
• Any information that you provide will be kept strictly confidential, except as required by law.
• Qualified health professionals will monitor your health as it relates to the study.

• Men and women aged 18-45 with or without Type 1 Diabetes
• Result of last HbA1c test must be less than 10% to participate
• Must not be currently doing more than 150 minutes of exercise per week
• Must not have severe diabetes retinopathy
• Must not have a history of keloid formation
• Must not have Type 2 Diabetes
• Must be able to attend 3 study visits at the research site over approximately 2-6 weeks

The study team will explain the research in its entirety but some details are:

• Participants will provide blood samples, undergo a physical examination, and a body composition assessment (DEXA). 2 of thevisits will entail physical exercise tests.
• Participants will use a glucose monitoring device over 10 days.
• Participants will undergo an exercise capacity test.

The Joslin Diabetes Center
The Joslin Diabetes Center is the world’s leading diabetes care and research center. Researchers at the Joslin Diabetes Center are passionate about improving the lives of people with diabetes, and believe that diabetes is a condition that can be managed without complications, and one day be cured.

Please note:
Due to the COVID-19 pandemic, the researchers would like to assure the participants that ensuring their and the study staff’s safety is of utmost importance