The AMAZES Study: Asthma and Macrolides: the Azithromycin Efficacy and Safety Study (Nedlands, Perth)

Please note: This trial has finished recruiting and is not accepting new participants.

Research Center: Sir Charles Gairdner Hospital
Location: Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands, Perth WA (click for map)
Lead Doctor: Clinical Associate Professor Alan James   
Ethics Committee: Approved by the Sir Charles Gairdner Group Human Research Ethics Committee


The AMAZES Study research team is aiming to determine whether taking an antibiotic (Azithromycin) alongside normal asthma medications helps to reduce the number of asthma ‘attacks’ and general daily symptoms experienced by adults with asthma. Eligible participants will be randomly allocated to take either Azithromycin or placebo tablets over a 48-week period (neither participants nor investigators will know which medication is being taken until the end of the study). Participants will have their asthma closely monitored over the 48-week period and monitoring will continue for an additional 4 weeks after the treatment has ended. Participants will not need to stop taking their regular asthma medication.

Who Can Participate?

  • Adults with asthma (aged 18 and over)
  • who are non-smokers (or ex smokers) and
  • who experience symptoms despite taking regular preventer medication

What Next?

  1. Click the link below to enter your contact details and answer some eligibility questions.
  2. The research centre will then contact you by phone to discuss the trial and answer your questions.
Click Here to Enter Your Contact Details and Be Contacted by Phone About the Trial

Is This Study Not For You?

Enter your details to be notified via email about new studies in your area