Research Center: Department of Psychiatry, NYU Langone Health
Location: 8th floor One Park Avenue between 32nd & 33rd Streets, New York, NY 10016
Lead Investigator: Charles Marmar, M.D.
IRB Committee: This study has been reviewed and approved by NYU Langone Health Institutional Review Board

Alcohol use disorder (AUD) has been found to frequently co-occur with post-traumatic stress disorder (PTSD). Research has shown that there is a link between how the brain responds to negative emotions (which is common in PTSD) and addiction (which is common in AUD).

This study is recruiting to find the effectiveness of an investigational drug, Topriamate,  on alcohol use disorder (AUD) co-occurring with post-traumatic stress disorder (PTSD). 

The study seeks adults aged 18 to 70 years old who are struggling with AUD co-occurring with PTSD. The study will run for approximately 4 months.

• You will help advance medical research.
• You may experience improvements to your alcohol use disorder.
• You may experience improvements to your post-traumatic stress disorder.
• You will be compensated for participating in this study, ranging from up to $595 or up to $745
• Reimbursement for travel, accommodation, and meals is available for in-person visits.
• Qualified health professionals will monitor your health as it relates to the study.

• If you decide to participate in a study and later feel that you no longer wish to be part of it, you may withdraw at any time.
• Your records relating to the study and any other information received will be kept strictly confidential, except as required by the law.

• Adults aged 18 to 70 years old who are experiencing symptoms of post-traumatic stress disorder and alcohol use disorder. 
• Must be able to attend the remote visits (through video or phone) and the in-person visits (4-6 visits at our office in midtown Manhattan).