Please note: This trial has finished recruiting and is not accepting new participants.

Research Center: Lindner Center of HOPE
Location: 4075 Old Western Row Rd Mason OH 45040
Lead Doctor: Dr. Susan L. McElroy
IRB Committee: This study has been reviewed and approved by the Western Institutional Review Board

Background

Major Depressive Disorder is a leading cause of disability in the United States. While there are options available, finding a treatment that works best for an individual can be a long and costly process. Many also find that their current treatment does not provide them adequate relief from their depression symptoms.

This study explores if a new investigational medication, Rapastinel, can treat symptoms of a major depressive episode while a participant is currently on a stable dose of another antidepressant therapy.

This study seeks men and women who currently suffer from MDD and are currently taking only one antidepressant. Participants are required to attend 11-12 study visits at the research site over approximately a 6 week period and will be reimbursed $75 per completed visit for travel and related expenses.

Why Participate?

• You will be helping to advance medical research.

Your Rights

• If you decide to participate in the study and later feel that you no longer wish to be part of it, you may withdraw at any time.
• Your records relating to this study and any other information received will be kept strictly confidential, except as required by the law.
• Qualified health professionals will monitor your health as it relates to the study.

Who Can Participate?

• Men and women aged 18-65 who are currently experiencing symptoms of MDD
• Are only taking one antidepressant.  
• Have felt depressed for at least 2 months
• Must be comfortable with needles
• Have not been diagnosed with Bipolar disorder, a Personality disorder or a psychotic disorder
• Are not currently participating in another clinical trial
• Able to attend 11-12 study visits at the research site over approximately 6 weeks