Research Center: University of Pittsburgh
Locations: Shadyside Medical Building 5200 Centre Avenue, Pittsburgh, PA, 15232 and Hillman Cancer Center, 5115 Centre Avenue, Pittsburgh, PA, 15232
Lead Investigators: Dr. Dana Bovbjerg and Dr. Frank Jenkins
IRB Committee: This study has been reviewed and approved by the University of Pittsburgh Institutional Review Board

Background

While stress is a natural reaction in our body to cope with the demand of the situation at hand, it has become a major contributor to chronic disease in today’s ever-changing world.

Researchers are attempting to understand how stress can impact our body including its ability to repair DNA damage in the blood cells. They are also exploring an FDA-approved medication (commonly used to treat high blood pressure) to see if it can influence an individual’s response to stress.

This study seeks healthy African American men and women who weigh at least 110 pounds. Participants are required to attend 3 study visits at the research sites over a 1 to 6 month period and will be compensated up to $205 for participating in this study.

Why Participate? 

• You will be helping to advance research on DNA damage and repair activity.
• You will be compensated up to $205 for participating in this study.
• Parking costs will be covered, or transportation costs will be reimbursed (up to $5 each study visit).

Your Rights

• If you decide to participate in the study and later feel that you no longer wish to be part of it, you may withdraw at any time.
• Your records relating to this study and any other information received will be kept strictly confidential, except as required by law.

Who Can Participate?

• Healthy African American men and women aged 20-59 
• Weigh at least 110 lbs.
• Able to attend 3 study visits at the research sites.
• Have normal blood pressure.
• Non-smokers, who do not use other nicotine-containing products