Research Center: Royal Brisbane and Women’s Hospital
Location: Butterfield St, Herston QLD 4029
Lead Doctor: Dr Robert Adam
Ethics Committee: This study has been reviewed and approved by The Alfred Human Research Ethics Committee

Background

Essential Tremor (ET) is a nerve disorder characterized by uncontrollable shaking, or “tremors,” in different parts and sides of the body. A tremor is an involuntary, rhythmic, movement of a body part. While current treatments are available, these medications do not provide patients long lasting results, with about 50% of patients return to experiencing symptoms and tremors.

This study is looking to understand if a new investigational medication can provide a long lasting response and well-tolerated option for those with essential tremor. This research study involves a study drug that is not approved by any regulatory agency, including Australia’s Therapeutic Goods Administration, so this research is therefore considered experimental. Information gathered from this study may help others with essential tremor in the future.

This study seeks men and women 18-75 who have been diagnosed with essential tremor for at least 3 years . Participants are required to attend 7 study visits at the research site over about a 3 month period. Study participants will not be able to drive a car, operate heavy machinery or engage in any other activity requiring mental alertness during the 28 days that they will be provided the study medication.

Why Participate?

• You will be reimbursed actual costs that you incur as a direct result of participating in this study, such as travel, parking, meals, etc.
• You will be helping to potentially find a medication that provides longer relief of symptoms for those diagnosed essential tremor.
• You will be helping to advance medical research.

Your Rights

• If you decide to participate in the study and later feel that you no longer wish to be part of it, you may withdraw at any time.
• Your records relating to this study and any other information received will be kept strictly confidential, except as required by law.
• Qualified health professionals will monitor your health as it relates to the study.

Who Can Participate?

• Men and women aged 18-75 (inclusive)
• Have been diagnosed with essential tremor for at least 3 years or more
• If taking medication(s) for essential tremor, must have been taking at least 1 month
• For those taking more than 1 medication for their essential tremor symptoms, you must be willing and able to stop taking all but 1 current medication for the duration of the study
• Able to attend 7 study visits at the research site over about 3 months
  • Please note that up to 4 of these study visits are Oovernight stays at the research site (meaning you will need to stay at the research site for 24 hours and not leave during that time)