Research Center: The University of South Florida
Location: 12912 USF Health Drive, STE 1400, Tampa FL, 33612
Lead Researcher: Dr. Christina McCrae
IRB: This study has been reviewed and approved by the USF Institutional Review Board

Currently taking opioid pain medication but want a safer, more sustainable way to manage your pain and sleep? This study may be a good fit.

Researchers at the University of South Florida are testing a non-drug sleep-focused treatment designed to improve sleep, ease pain, and support participants in safely tapering opioids with medical guidance.
This research study includes expert support, no-cost treatment, tapering assistance, and health assessments.

Improve sleep. Reduce pain. Get support tapering opioids. Get paid.

Participants can receive up to $600 in electronic gift cards, and travel compensation will also be provided. If you’re 18 or older, currently prescribed opioid pain medication, and open to better sleep and lower opioid use, click below to see if you qualify!

• Participants will explore a new potential treatment for chronic pain at no cost.
• Participants will be compensated up to $600 in electronic gift cards for participating in this study. Travel compensation will also be provided.
• Participants may experience improvements in their sleep, which could help them better manage pain during the study.
• Participants will be contributing valuable information that may benefit those experiencing chronic pain in the future.
• Participants will be helping to advance medical research.

• You will receive a detailed outline of all details of the study, including treatment, risks, and procedures, and you will be given the chance to ask study staff questions before you decide whether to participate.
• If you decide to participate in the study and later feel that you no longer wish to be part of it, you can withdraw at any time
• Your records relating to this study and any other information received will be kept strictly confidential, except as required by law.

Who Can Participate:

• Must be 18 years or older
• Must be able to read and understand English
• Must have been prescribed an opioid medication (e.g., Codeine, Tramadol, Morphine, Fentanyl, Oxycodone) for 1+ months
• Must take this opioid medication on 3 or more days each week
• Must have a desire to reduce or eliminate opioid use
• Must have chronic widespread pain for 3+ months
• Must struggle with sleep (difficulty falling or staying asleep, even with adequate opportunity for sleep)
• Must be able and willing to participate in all study procedures over 49 weeks

Who Cannot Participate:

• Must not have a seizure disorder
• Must not be participating in another non-pharmacological trial for pain, sleep, or mood outside this study
• Must not be pregnant
• Must not have had surgery within the last 6 months
• Must not have severe foot neuropathy as the main cause of pain

University of South Florida
Led by outstanding faculty and professional staff, the University of South Florida conducts innovative scholarship, creative activity, and basic and translational research, and delivers a world-class educational experience promoting the success of our talented undergraduate, graduate, and professional students. As a public metropolitan research university, USF, in partnership with its communities, serves the people of Florida, the nation, and the world by fostering intellectual inquiry and outcomes that positively shape the future – regionally, nationally, and globally.

The study team will explain the research in its entirety, but some details include:

• Participants will complete a few scheduled assessments over the 49-week study (baseline, after sleep treatment, after tapering, and a 6-month follow-up).
• Participants will take part in a behavioral sleep treatment (which may be completed online) and an individualized opioid tapering plan based on their needs.
• Some procedures, such as occasional fMRI scans, wearing an actigraphy watch, or completing an at-home sleep study (PSG), will take place only at specific timepoints.
• Participants will complete brief online sleep diaries and surveys at set intervals, and may occasionally be asked to provide a urine sample.