Explore the Future of Cancer Detection and Women’s Health with UBC Researchers!


Next Steps

  1. Complete the study questionnaire
  2. Understand if you’re eligible to participate
Click Here

Research Center: University of British Columbia
Location: This study is conducted virtually across British Columbia
Lead Researchers: Aline Talhouk, Jessica McAlpine, and Andrea Neilson
IRB: This study has been reviewed and approved by the UBC/BC Cancer Research Ethics Board

About the Study

Are you aware that an estimated 1 in 2 women will face a cancer diagnosis in their lifetime? In response to these alarming statistics, the University of British Columbia is spearheading the RESToRE study, a groundbreaking initiative aiming to transform early cancer screening and prevention.

This study examines the feasibility and acceptability of innovative approaches, delving into the complex interplay of cancer risk factors. The overarching goal is to enhance screening precision, improve accessibility to prevention measures, and alleviate the strain on health resources. Join researchers as they reshape the landscape of cancer prevention and make a lasting impact on women’s health, today!

Why Participate?

  • Participants have the chance to take part in a 4-week nutrition and exercise program with a coach.
  • Participants will receive $20 electronic gift card to account for any out-of-pocket costs.
  • Participants may receive an early diagnosis of an underlying pathology.
  • Participants will be contributing valuable information that may benefit the future of women’s health.
  • Participants will be helping to advance prevention research on uterine cancer.

Your Rights

  • If you decide to participate in the study and later feel that you no longer wish to be part of it, you can withdraw at any time.
  • Any information that you provide will be kept strictly confidential, except as required by law.
  • Qualified health professionals will monitor your health as it relates to the study.

Who Can Participate?

  • Must be postmenopausal
  • Must not have had a period for at least 3 years
  • Must not currently be on any hormonal therapy or using an intrauterine device (IUD)
  • Must not have had a hysterectomy
  • Must not have recently experienced any abnormal uterine bleeding (menstrual bleeding, including spotting, after menopause)
  • Must not currently be receiving any chemotherapy or pelvic radiation therapy
  • Must be able to virtually participate in this study for 7 virtual study visits for approximately 2 months

More Study Details

The study team will explain the research in its entirety but some details are:

  • Once a participant provides consent, the study coordinator will help them download a mobile app called MyCap, to keep track of their participation in the study. Non-app communication is available via email or phone calls if preferred. In addition, our study physicians will be connecting with the indicated primary care provider, if applicable, to ensure they are aware of participation in the study and address any concerns.
  • Participants will take part in the Progesterone Challenge Test. Once researchers receive confirmation that a primary care provider or a gynecologist is supporting their participation, researchers will ask that they contact them to schedule an appointment. During the medical appointment, the doctor will explain the Progesterone Challenge Test, review what to expect, and prescribe an oral medication (medroxyprogesterone acetate). Please indicate when this prescription is received on MyCap, and do not start the Progesterone Challenge Test until the next step is completed (at-home tampon and vaginal swabs).
  • Once the at-home vaginal sample collection is completed and the samples are sent back, the next step will be to start the Progesterone Challenge Test. Participants will be asked to take the prescribed oral medication once a day, for ten (10) days. Researchers will send reminders through the MyCap app, which will also allow participants to track the days of the Progesterone Challenge Test.

About the Research Center:

University of British Columbia
The University of British Columbia is a global centre for teaching, learning, and research, consistently ranked among the top 50 public universities in the world. UBC embraces innovation and transforms ideas into action. Since 1915, UBC has been opening doors of opportunity for people with the curiosity, drive, and vision to shape a better world.

Please note:
Due to the COVID-19 pandemic, the study will be conducted remotely which means there will be no in-person visits, allowing you to participate in the comfort of your own home.

What’s Next?

  1. Click the link to enter your contact details and take the study questionnaire.
  2. If eligible, further instructions on how to proceed will be provided to you.
Click Here to Check Your Eligibility for This Study

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