Research Centre: Peninsula Therapeutic And Research Group
Location: 137 Frankston – Flinders Rd, Frankston VIC 3199, Australia
Lead Researcher: Dr. Jennifer Grunfeld
HREC: This study has been reviewed and approved by the Bellberry Human Research Ethics Committee

Have you ever experienced a panic attack or been diagnosed with panic disorder? If so, you may be interested in a new research study investigating the safety and effectiveness of a potential new treatment for panic disorder. This study is testing an experimental medication combining two known, approved medications.

This study seeks to determine whether this potential new medication can help individuals manage their panic symptoms. By joining, participants can contribute to valuable research that may pave the way for improved treatments for panic disorder and related conditions. Your mental health is important—see if this study could be right for you.

• Participants may receive a new potential treatment for panic disorder at no cost.
• Participants may experience improvements in their panic disorder symptoms.
• Participants will be contributing valuable information that may benefit those with panic disorder in the future.
• Participants will be helping to advance medical research.
• Participants will receive a small payment for their time and effort in this study, as well as reimbursement for any travel-related expenses.

• If you decide to participate in the study and later feel that you no longer wish to be part of it, you can withdraw at any time.
• Any information that you provide will be kept strictly confidential, except as required by law.
• Qualified health professionals will monitor your health as it relates to the study.

• Men and women aged 18-65 who are diagnosed with panic disorder or who have had experience with panic attacks and think they may have panic disorder
• Individuals who experience regular unexpected panic attacks (an unexpected panic attack is a panic attack that doesn’t have a trigger. It comes on out of the blue—that is, in situations where you didn’t expect to feel nervous or uncomfortable)
• Individuals can not be taking benzodiazepines (e.g Alprazolam, Diazepam, Oxazepam, Temazepam, Clonazepam, Lorazepam)
• Individuals can not have a diagnosis of obsessive-compulsive disorder (OCD), bipolar disorder, schizophrenia, or severe agoraphobia
• Participants need to be able to attend 6 study visits at a mental health clinic in Frankston over 14 weeks.

The study team will explain the research in its entirety but some details include:

• This is a placebo-controlled study and may not be of any benefit to individuals.
• Participants will be asked to provide informed consent, medical history, and demographic information and undergo an eligibility assessment.
• Participants will undergo assessments of their physical and mental health, physical examinations, blood and urine tests, and ECGs.
• Participant’s physical and mental health will be monitored throughout the study.
• Study team will provide feedback to your GP.

Peninsula Therapeutic And Research Group (PTRG)
PTRG is a clinical research unit specialising in mental health studies. With over 20 years of clinical trial experience, its team of doctors, nurses, clinical researchers, and administrative staff is dedicated to delivering the highest level of care. PTRG provides patients with access to clinical research opportunities involving potential new treatments.