4-Week Study on a New Potential Treatment for Adults with Obstructive Sleep Apnoea

Research Center: Woolcock Institute of Medical Research
Location: 431 Glebe Point Road Glebe NSW 2037 Sydney, Australia
Principal Investigator: Prof. Ron Grunstein
IRB Committee: This study has been reviewed and approved by Southern Adelaide Clinical HREC


Obstructive sleep apnoea (OSA) is a sleep disorder that makes breathing difficult during sleep and contributes to being tired even after a full night’s sleep. Currently, there are limited therapies available for OSA. Continuous positive airway pressure (CPAP) is one but it often has poor tolerance and compliance as it can be  cumbersome, restrictive and uncomfortable to sleep with. As such there is a clear need for alternative therapies for OSA with medications which are more user friendly.

This study seeks to investigate the effectiveness of a potential treatment for obstructive sleep apnoea over approximately 4 weeks. Researchers hope to find an alternative pharmaceutical treatment for obstructive sleep apnoea.

This study seeks adults aged 18-65 years old who have been diagnosed or are currently in the process of being diagnosed with obstructive sleep apnoea. Participants are required to take the investigational treatment for 4 weeks, attend 2-3 sleep study stays and one 3-hour day visit at the Adelaide Institute for Sleep Health (AISH). 

Why Participate? 

  • You may experience improvements to your sleep apnoea symptoms.
  • You will contribute to the development of a potential treatment to help people with sleep apnoea.
  • You will be compensated approximately $500 for participating in this study.
  • You may be provided with a copy of the sleep study results at your request.
  • You will be helping to advance medical research. 

Your Rights

  • If you decide to participate in the study and later feel that you no longer wish to be part of it, you may withdraw at any time.
  • Your records relating to this study and any other information received will be kept strictly confidential, except as required by the law.
  • Qualified health professionals will monitor your health as it relates to the study.

Who Can Participate?

  • Adults aged 18 to 65 years old who have been diagnosed or are currently in the process of being diagnosed with obstructive sleep apnoea
  • Are not currently using CPAP consistently (on average more than 4 hours for at least 5 nights a week) 
  • Able to take the investigational treatment and attend 2-3 sleep study stays at the Adelaide Institute for Sleep Health (AISH) over approximately 1 month

What Next?

  1. Click the link below to enter your contact details and answer some eligibility questions.
  2. The research centre will then contact you by phone to discuss the trial and answer your questions.
Click Here to Enter Your Contact Details and Be Contacted by Phone About the Trial

Is This Study Not For You?

Enter your details to be notified via email about new studies in your area