Research Center: Rutgers University, New Brunswick, New Jersey
Location: 57 US Highway 1. New Brunswick, NJ 08901-8554.
Lead Researcher: Steven Malin
IRB: This study has been reviewed and approved by the Rutgers Institutional Review Board

Type 2 diabetes affects millions of people worldwide, and its impact on vascular health can lead to serious complications. Researchers are exploring how exercise, insulin, and tiny cellular particles called extracellular vesicles (EVs) influence vascular health.

This study seeks to better understand these interactions in healthy adults and those with obesity. To qualify, participants should not currently exercise regularly or should have exercised less than 90 minutes per week over the past 6 months.

Take the first step today!

• Participants will be compensated between $250 and $500 for participating in this study. Compensation will only be provided to eligible participants who complete the study.
• Participants will be contributing valuable information that may benefit those with type 2 diabetes in the future.
• Participants will be helping to advance medical research.

• If you decide to participate in the study and later feel that you no longer wish to be part of it, you can withdraw at any time.
• Any information that you provide will be kept strictly confidential, except as required by law.
• Qualified health professionals will monitor your health as it relates to the study.

• Individuals aged between 40 and 70 years old
• Must not have lost or gained more than 2kg within the past 6 months
• Must not have been diagnosed with type 1 diabetes
• Must not be on insulin therapy
• Must not have smoked in the last 5 years
• Must not currently be exercising actively or engaging in more than 90 minutes of exercise per week for the past 6 months

The study team will explain the research in its entirety but some details are:

• Participants will be asked to complete informed consent, undergo a blood draw, provide history and physical, urine collection, and body fat measurement (waist/hip circumference, DXA).
• Participants will be asked to participate in VO2max treadmill testing, blood pressure, AI, CEU, PWV tests, FMD, CCA-IMT, diet records, appetite and quality of life surveys, and the NIH Toolbox.
• Participants may be asked to wear an accelerometer and heart rate monitor, and engage in a 16-week exercise training program (3 times per week) at the Institute for Food, Nutrition, and Health at Rutgers University with a personal trainer.

Rutgers University

Rutgers, The State University of New Jersey, stands among America’s highest-ranked, most diverse public research universities. The oldest, largest, and top-ranked public university in the New York/New Jersey metropolitan area, you’ll find us at our main locations in three New Jersey cities, and our footprint can be seen around the region. We’re an academic, health, and research powerhouse and a university of opportunity.