Research Center: University of California San Diego
Location: Altman Clinical and Translational Research Institute (ACTRI) 9452 Medical Center Dr La Jolla, CA 92037
Lead Researcher: Dr. Atul Malhotra
IRB: This study has been reviewed and approved by the UCSD Institutional Review Board

Living with both COPD and sleep apnea? These conditions create unique challenges, affecting breathing, causing fatigue, shortness of breath, and poor sleep. Managing them can feel overwhelming, leaving many feeling isolated and longing for relief.

This study aims to deepen the understanding of these conditions by comparing adults with these conditions to those with COPD or sleep apnea alone. Researchers will explore the effects of different treatments on these conditions, helping to improve future care and outcomes for those affected.

Interested? See if you qualify for this study!

• Participants in this study will have the opportunity to try a new potential therapy for COPD at no cost.
• Compensation ranges from $275 to $925 for completing all study activities. If a participant ends the study early, they will be compensated based on the visits completed, but no compensation will be provided for missed visits.
• Free parking is available, and participants will be reimbursed for minor out-of-pocket expenses, such as meal vouchers, public transportation, or taxi fares. Lyft pickup/drop-offs are also available if needed.
• Participants may experience improvements in their COPD symptoms while contributing valuable information that could benefit others with the condition in the future.
  Participants will help advance medical research.

• If you decide to participate in the study and later feel that you no longer wish to be part of it, you can withdraw at any time.
• Any information that you provide will be kept strictly confidential, except as required by law.
• Qualified health professionals will monitor your health as it relates to the study.

• Men and women aged 40 to 79 who have been diagnosed with either chronic obstructive pulmonary disease (COPD) alone OR both COPD and obstructive sleep apnea (OSA)
• Must be postmenopausal and must not be pregnant, breastfeeding, or planning to become pregnant
• Must not be currently receiving continuous oxygen therapy for COPD or using PAP treatment for OSA
• Must not have smoked tobacco in the past six months
• Must not be allergic to MRI contrast (gadolinium)
• Must be willing and able to comply with the study requirements and procedures

The study team will explain the research in its entirety but some details are:

• Participants will be asked to attend a daytime visit.
• Participants will be asked to undergo an overnight sleep study.
• Participants will be asked to participate in a cardiac MRI session.

University of California San Diego
Recognized as one of the top 20 research universities worldwide, the University of California San Diego fosters a culture of collaboration that drives discoveries, advances society and boosts economic impact. The institution prioritizes providing students with opportunities to become changemakers, equipping them with multidisciplinary tools to address the world’s most pressing challenges.