Research Centre: Flinders Medical Centre
Location: Room 6R347 Flinders Medical Centre, 1 Flinders Drive, Bedford Park, Adelaide SA 5042
Lead Researcher: Associate Professor Carmine De Pasquale
HREC Committee: This study has been reviewed and approved by Bellberry Limited Human Research Ethics Committee

Heart failure does not mean that the heart has stopped working and cannot be treated. It merely means that the heart is unable to (function) pump blood at an optimum rate. The body relies on the heart’s pumping ability to maintain normal body functions. During heart failure, because of the weakened state of the heart, it is unable to supply enough blood to vital cells and organs. This makes doing everyday activities difficult. 
Currently, there are no approved therapies for heart failure that would help improve the heart’s pumping action without causing significant complications. This study hopes to find an alternative treatment that may help reduce further complications and hospitalisations that may be a result of heart failure symptoms. 

Interested participants must be aged 40 years old or older who have been diagnosed with heart failure. 

• You may experience potential improvements to the symptoms you are experiencing, although this is not guaranteed. 
• You may contribute valuable information that may benefit others in the future.
• You may help develop a potential alternative treatment for heart failure that is not yet commercially available. 
• You will be reimbursed for each in-person visit to cover for your travel and incidental expenses. 
• You will be helping to advance medical, specifically heart health-related, research.

• If you decide to participate in the study and later feel that you no longer wish to be part of it, you may withdraw at any time.
• Your records relating to this study and any other information received will be kept strictly confidential, except as required by the law.
• Qualified health professionals will monitor your health as it relates to the study.

• Adults aged 40 years old or older who have been diagnosed with heart failure. Adults who are hospitalised can also participate in this research study.
• Interested participants must have been treating their condition with diuretics for at least the last month.
• Interested participants must be able to attend 7 study visits at the research site during the first year and then 3 study visits during the second year onwards, with telephone calls in between the study visits starting from the 12 month onwards. This study will take place for over approximately 2-3.5 years. 
• Interested participants must be willing to take the study treatment as instructed by the study team.

Flinders Medical Centre (FMC)
Flinders Medical Centre (FMC) is the southern area’s largest hospital and provides medical services for people living in the southern metropolitan area of Adelaide. Since opening in 1976, FMC has earned an international reputation as one of Australia’s finest public teaching hospitals and as a centre for research excellence. FMC and more than 5,000 skilled staff provide an extensive range of services for patients of all ages.

Please note:

Due to the current situation with the COVID-19 pandemic, the researchers would like to assure the participants that ensuring the safety of the participants as well as the study staff is of utmost importance.