“Please note: This trial has finished recruiting and is not accepting new participants.”
Research Center: University of Oklahoma Health Sciences Center (OUHSC)
Location: 755 Research Parkway, Suite 150, Oklahoma City, OK 73104
Lead Researcher: Amy M. Cohn, PhD
IRB Committee: This study has been reviewed and approved by the University of Oklahoma Health Sciences Center (OUHSC) Institutional Review Board (IRB #: 11865)
Background
According to the Centers for Disease Control and Prevention (CDC), smokers are defined as people who smoke at least 100 cigarettes during their lifetime or those who smoke every day or some days. The CDC also reported that in 2019, almost 14 out of 100 U.S. adults aged 21 years or older smoked cigarettes. This means a predicted 34.1 million adults in the United States currently smoke cigarettes.
This study seeks to understand the perspectives of smoking low nicotine cigarettes among adult smokers. Researchers are interested in how smoking these cigarettes affects their smoking pattern, feelings and attitudes. This study is not going to ask its participants to quit smoking. However, the results from this study could help in the prevention and regulatory decisions on cigarettes.
Researchers are inviting adults aged 21 to 26 years who smoke cigarettes. Participants must be willing to comply with all the necessary study requirements. Compensation will be available to eligible individuals for participating in this study.
Why Participate?
- You may have an increased understanding of why you use cigarettes.
- You may contribute valuable information that may benefit others in the future.
- You will be compensated up to $551 for participating in this study.
- You will be helping to advance medical research and policies aimed at reducing health consequences associated with smoking.
- You will be provided with study cigarettes at no cost. These study cigarettes are experimental.
Your Rights
- If you decide to participate in the study and later feel that you no longer wish to be part of it, you may withdraw at any time.
- Your records relating to this study and any other information received will be kept strictly confidential, except as required by law.
- Qualified health professionals will monitor your health as it relates to the study.
Who Can Participate?
- Adults aged 21 to 26 years old who smoke cigarettes somedays or everyday in the past 3 months.
- Participants that have no intention to quit smoking.
- Participants must be willing to stop using nicotine/tobacco products at least 12 hours before attending study visits.
- Participants must be willing to abstain from caffeine for at least 1 hour before attending study visits.
- Participants must be able to attend 5 study visits for over approximately 2 months.
- These study visits may either be conducted at the research site or through virtual means and take up to 2 hours per visit.
- Participation will also involve answering questionnaires and doing tasks during the study visits.
- Participants will need to complete daily surveys about their mood and smoking behavior on a smartphone.
- Participants must be willing to meet with study personnel for a curb-side pick-up/drop-off of the study cigarettes. Reimbursement for travel is provided.
About the Research Center

Every day, the University of Oklahoma Health Sciences Center educates more than four thousand students and residents to strengthen our state’s healthcare workforce; discovers new treatments for disease; and provides Oklahomans a unique resource for highly skilled, compassionate care across all children’s, women’s and adult specialties. OUHSC is dedicated to improving the quality of life for those we serve — both today and for future generations.
Please note:
To prioritize the participants’ and the study team’s health, the sequence of study requirements may vary due to COVID-19 rules and guidelines set by authorities at the National, Local, or University level. This may mean that the in-person study visits may become virtual (e.g. online video calls) visits. The study team can explain further on this.