The AMAZES Study: Asthma and Macrolides: the Azithromycin Efficacy and Safety Study (New Lambton Heights, Newcastle)
Please note: This trial has finished recruiting and is not accepting new participants.
The AMAZES Study research team is aiming to determine whether taking an antibiotic (Azithromycin) alongside normal asthma medications helps to reduce the number of asthma ‘attacks’ and general daily symptoms experienced by adults with asthma. Those patients for whom this study is suitable, will be randomly allocated to take either Azithromycin or placebo tablets over a 48-week period (neither participants nor investigators will know which medication is being taken until the end of the study). Participants will have their asthma closely monitored over the 48-week period and monitoring will continue for an additional 48 weeks after the treatment has ended. Participants will not need to stop taking their regular asthma medication.
Who Can Participate?
- Adults with asthma (aged 18 and over)
- who are non-smokers (or ex smokers) and
- who experience symptoms despite taking regular preventer medication