Research Center: The University of Sydney
Location: Royal North Shore Hospital, Reserve Rd, St Leonards NSW 2065
Lead Researchers: Maliheh Ghadiri, Larissa Gomes dos Reis
Ethics Committee: This study has been reviewed and approved by the Northern Sydney Local Health District Human Research Ethics Committee, reference: HREC/16/HAWKE/256

Background

Chronic sinus infection is when patients have excessive mucus, abnormal sinus structure and bacteria infection resulting in severe pain and discomfort is difficult to treat with current therapy and in many cases, requires surgical intervention.

Researchers have been trying to develop new technologies and devices to specifically target the nasal sinuses to better treat sinusitis (inflammation of the sinuses) caused by bacterial infections. A device that could target the sinus cavity will particularly be useful for the treatment of chronic sinusitis.

This study will help researchers to develop a nasal nebuliser to deliver medicines to the nose, which could potentially be used for the treatment of chronic sinus infection in the future.

This study seeks  healthy men over 20 years of age who do not have a history of chronic sinus infection or severe allergies to explore this new investigational device. Participants are required to attend 4 study visits at the research site over a 2 month period and will be compensated $250 for completing the study.

Why Participate?

• Your participation will help improve future treatment for patients with chronic sinus infection
• You will be compensated $250 for completing this study

Your Rights

• If you decide to participate in the study and later feel that you no longer wish to be part of it, you may withdraw at any time.
• Your records relating to this study and any other information received will be kept strictly confidential, except as required by the law.
• Qualified health professionals will monitor your health as it relates to the study.

Who Can Participate?

• Healthy men aged 20+
• Caucasian
• No history of smoking
• Do not have a history of chronic sinus infection or rhinitis
• Do not have severe or multiple allergies including hayfever
• Able to attend 4 study visits at the research site over approximately 2 months