Please note: This trial has finished recruiting and is not accepting new participants.

Research Center: Royal Adelaide Hospital/University of Adelaide
Location: Adelaide Health & Medical Sciences Building, University of Adelaide, Cnr North Terrace and George Street, Adelaide SA
Lead Researcher: Professor Karen Jones, Professor Michael Horowitz, Professor Chris Rayner, Dr Chinmay Marathe, Ms Seva Hatzinikolas and Mrs Rachael Tippett
Ethics Committee: This study has been reviewed and approved by the ethics committees of the Royal Adelaide Hospital and University of Adelaide

Background

Exenatide BD (known as Byetta®), taken twice daily, is a drug that is commonly used in the management of type 2 diabetes by reducing blood sugar levels. Exenatide BD works primarily by slowing the rate at which the stomach empties food.

A once weekly dose of exenatide (Exenatide QW or Bydureon®) is now available. This study aims to determine the effect of Exenatide QW on the rate of stomach emptying and blood sugar levels after a meal.

This study seeks healthy men and post-menopausal women aged 55 – 70 years old who would like to help advance medical research. Volunteers are required to attend 11 study visits at the research site over ~11  weeks and will receive an honorarium of $18 per hour for their participation in this study.

Benefits of Participation

• Involvement will advance medical research by providing valuable information about the mechanism of action of this diabetic medication.
• Volunteers  will receive an honorarium of $18/hour (~$310 for the entire study).

Your Rights

• If you decide to participate in the study and later feel that you no longer wish to be part of it, you may withdraw at any time without prejudice.
• Your records relating to this study and any other information received will be kept strictly confidential, except as required by the law.
• Qualified health professionals will monitor your health as it relates to the study.

Who Can Participate?

Healthy men and post-menopausal women (for at least 1 year):

• Aged 55 – 70 years
• Body mass index (BMI) 25 – 35kg/m²
• Non diabetic
• Not a vegetarian
• Not taking blood thinners
• Able to attend 11 study visits at the research site over ~11 weeks