Please note: This trial has finished recruiting and is not accepting new participants.

People with heart and chronic kidney disease often have inflammation. Inflammation is important to the healing process, but long term inflammation that goes unchecked can potentially cause heart attack and stroke. 

Researchers working with Novo Nordisk are conducting a research study with an investigational new medication, for people with inflammation, heart and chronic kidney disease. 

Are you interested in potentially joining this research study?

• Participants will receive the investigational medication at no cost to themselves.
• Participants may experience improvements in their symptoms of their condition. 
• Participants will be contributing valuable information that may benefit those with inflammation, heart and chronic kidney disease in the future and reduce the chance of complications.
• Participants will be helping to advance medical research.

• If you decide to participate in the study and later feel that you no longer wish to be part of it, you can withdraw at any time.
• Any information that you provide will be kept strictly confidential, except as required by law.
• Qualified health professionals will monitor your health as it relates to the study.

• Individuals aged 18 and above who are diagnosed with:
  • Heart attack (myocardial infarction) or
  • Stroke (cerebrovascular accident)or
  • Poor circulation 
  • And reduced kidney function
• Must not have a history of untreated latent tuberculosis
• Able to attend the research site every quarter over approximately 4 years

The study team will explain the research in its entirety but some details are:

• Up to 9 visits during the first year then once quarterly
• This is a double blind placebo controlled study
  • A double-blind study is a type of clinical trial in which neither the participant nor the researcher knows which treatment or intervention participants are receiving until the clinical trial is over
  • This means you will be randomly given either the study medication or a placebo

This research study is taking place in several locations. To see if there is a research site near you, please see below. 

Research Site 1: St. Vincent’s Hospital
Location: 4th Floor Daly Wing, 35 Victoria Parade Fitzroy
Lead Researcher: Prof Richard MacIsaac

The Department of Endocrinology and Diabetes is part of the Tertiary Hospital of St Vincent’s Hospital Melbourne.
It is involved in and leading in many clinical trials for Type 1 and Type 2 Trials both investigator initiated and sponsor lead trials.

Research Site 2: Monash Health Nephrology and Monash Heart
Location: Level 3, 246 Clayton Road, Clayton, VIC, 3168
Lead Researcher: Professor Peter Kerr

We are two leading research departments within a large tertiary hospital. Consisting of Nephrology and Cardiology, we are dedicated and hardworking teams. Specialising in all phases of clinical trials regarding heart and kidney disease.

Research Site 3: Royal Adelaide Hospital
Location: Port Rd, Adelaide SA 5000, Australia
Lead Researcher: Associate Professor Matthew Worthley

The Cardiometabolic research department is a large Research department that specialises in all aspects of Cardiometabolic Clinical Trials. We are a dedicated team of highly experienced clinical researchers consisting of both Cardiologists, Endocrinologists, Renal physicians and Registered Nurse Coordinators.
We are located within the Royal Adelaide Hospital which does more Clinical Research than any other Hospital in Australia.

Research Site 4: Barwon Health, Geelong Cardiology Research Unit
Location: Level 2, Little Ryrie St., Geelong VIC 3200
Lead Researcher: Associate Professor John Amerena

Making up the research unit are a dedicated team of healthcare professionals, including a number of highly experienced clinical trial coordinators and a medical research fellow.

Research Site 5: The Canberra Hospital
Location: Clinical Trials Support Unit, Canberra Hospital Garran ACT 2605
Lead Researcher: Professor Walter Abhayaratna

Clinical Trials Support Unit is part of Canberra Health Services. It conducts and supports several clinical studies across ACT.

Research Site 6: Advara Heartcare
Location: Shenton House, 57 Shenton Avenue, Joondalup WA 6027
Lead Researcher: Dr. Peter Purnell

Heartcare research has been conducting clinical trials since 2003 across all areas of cardiology. In excess of 30 clinical trials spanning arrhythmia, cholesterol management , anticoagulation, stroke risk, diabetes, weight loss, heart failure and underlying inflammatory disease.