Research Center: Zen Dermatology (Integrative Skin Science and Research)
Location: 4801 J St. Sacramento, CA 95819
Lead Researcher: Raja Sivamani, MD, MS, AP
IRB Committee: This study has been reviewed and approved by the Allendale Institutional Review Board

About the Study

Dealing with wrinkles can be frustrating, but did you know that soybeans can help you regain a youthful appearance? Soybeans are a primary source of isoflavones, which can increase your skin’s collagen and moisture content. They can help fight dark spots, reduce wrinkles, and give you smoother, more youthful-looking skin.

If you’re interested in learning more about the skin benefits of isoflavones, this research study might be for you. This study seeks to investigate the effects of isoflavone supplementation on skin’s wrinkles, collagen, and pigment. It also seeks to understand its effects on skin and gut health, which in turn may help people make better decisions on using isoflavone skincare products. 

Why Participate? 

• Participants may receive a new potential isoflavone supplement at no cost.
• Participants may experience improvements in their skin and gut health. 
• Participants will be contributing valuable information that may benefit those who are interested in using isoflavone skincare products in the future.
• Participants will be compensated up to $270 for participating in this study. Compensation will only be provided for each completed study visit eligible participants attend.
• Participants will be helping to advance skin and gut health medical research.

Your Rights

• If you decide to participate in the study and later feel that you no longer wish to be part of it, you can withdraw at any time.
• Any information that you provide will be kept strictly confidential, except as required by law.
• Qualified health professionals will monitor your health as it relates to the study.

Who Can Participate?

• Women aged 50-70 who have been postmenopausal for more than 1 year
• Must not be taking any hormone replacement therapy
• Must not be allergic to soy or milk products
• Must be able to attend 5 study visits at the research site over approximately 25 weeks

Key Study Details 

The study team will explain the research study in its entirety but some details are:

• Each study visit will take about 1 to 1.5 hours. 
• Participants will be randomly assigned to 2 groups. One group will receive an isoflavone powder supplement, while the other will receive a casein powder supplement. 
• Participants will be asked to keep all used product packaging, including leftover protein powder supplements, and return them at each study visit.
• Participants will be given a log to track their daily intake of isoflavone or casein supplements. They will also be asked to complete questionnaires on their health and quality of life. 
• Participants will be asked to maintain their regular dietary patterns and habits throughout the study. 
• Participants will be asked to avoid self-tanning, spa tanning, or artificial tanning, and soybean or soy products throughout the study. 

About the Research Center:

Zen Dermatology

Zen Dermatology is a comprehensive medical aesthetic and integrative medical practice. They offer a unique all-in-one comprehensive inside/out approach to skin health, beauty, and wellness, in a high-end professional and zen-like atmosphere. Using skin beauty and wellness as a motivator, their goal is to engage both the individual and the local community in a new way of wellness, utilizing a combination of cutting edge medical and cosmetic procedures, holistic and complementary interventions, and clinical research to help you achieve optimal results.

Please note:
Due to the COVID-19 pandemic, the researchers would like to assure the participants that ensuring their and the study staff’s safety is of utmost importance.